BUTARE, RWANDA – BERLIN
AMR NETWORK

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PARTNERSHIPS

PARTNERSHIP BETWEEN:

Charité – Universitätsmedizin Berlin, Institute of Tropical Medicine and International Health / Germany

&

International Health and University Teaching Hospital of Butare / Rwanda (CHUB)

Tackling antimicrobial resistance in Africa – a global problem of unknown dimensions

Bacteria and other germs adapt when they are exposed to anti-microbial treatments such as antibiotics. This results in resistance against the substances used and medications lose their effect. Antimicrobial resistance (AMR) can render it impossible to treat common infections and leads to substantially increased healthcare costs, prolonged treatment, disability and death. AMR is a global problem and thus needs to be tackled globally. It exists in every country.

MORE ABOUT RWANDA

  • Rwanda is a small land-locked country in east-central Africa with a population of 11.9 million living on an area of 26,338 km².
  • Rwanda makes strong efforts to strengthen its economy, with coffee and tea production among its main exports.
  • The World Bank has praised Rwanda’s “remarkable development successes”, which have helped reduce poverty and inequality.
  • Life expectancy at birth in Rwanda is 66 (m) / 70 (f) years.
  • The probability of dying before the age of five is 35 for 1,000 live births.
  • Recovering after a terrible genocide (1994), Rwanda makes strong efforts to strengthen its economy, with coffee and tea production among its main exports.

 

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The main causes of this development are the overuse of antimicrobial medicine – especially in agriculture and animal farming – and unnecessary prescriptions for patients. Inappropriate use, wrong dosage, and lack of knowledge by medical doctors and patients alike aggravate the problem. A contributing factor is non-targeted antibiotic therapy in absence of microbiological results. The extent of AMR in low- and middle-income countries (LMIC) is largely unknown, mainly because relevant data are missing.

This is also the situation in Rwanda, which is facing the continuous development of antibiotic resistance against available antibiotics. And, as in many LMIC, the extent of the problem is unknown for lack of data.

Against this backdrop, more information is needed about the regional and local pathogen and resistance situation. This information will allow medical professionals to choose the right antibiotic and the government to develop and adapt local, national and regional treatment guidelines.

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The government of Rwanda has recognised the need for improving this situation.

Based on this national as well as existing international commitment, the two partnering universities have decided to tackle this important public health problem and join the global efforts to stop further development of antimicrobial resistance.

Joint efforts include the establishment of a data collection system, a surveillance system, the training of laboratory personnel to identify bacteria causing clinically relevant infections and possible resistance against the available antibiotics, and training of medical doctors to handle antibiotic treatment responsibly and based on the information available. The partnership is also supporting the Rwandan government in the development of standard treatment guidelines based on the data collected.

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eHEALTH

Our eHealth Contribution

One important problem identified is inadequate communication between the medical doctors caring for patients and the laboratories performing the required analyses. The requests for testing are paper-based and frequently get lost with the respective specimens on their way to the laboratories, or are severely delayed. The same applies to test results: These often reach the doctor late or never, making it impossible to base clinical decisions on them.

Therefore, the partnership decided to use an innovative approach and develop together with IT specialists an app-based system for communication between the laboratory and medical doctors. This will ensure timely delivery of the request and of the test result as well as the collection of valid data for subsequent analyses and the development of local evidence-based guidelines.

All tools developed consist of free and open-source software which has been adapted in teamwork with neighbouring African regions. Six HKP-supported partnerships collaborate closely because they use the same approach. This collaboration calls itself the COMBAT AMR network.

The COMBAT AMR network enables comparing and sharing as well as joint discussions on data, exchange of experiences and discussions on possible solutions. The network develops regional recommendations on AMR, and it creates substantial synergies.

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PARTNERSHIPS

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Charité – Universitätsmedizin Berlin / Germany

Charité – Universitätsmedizin Berlin, a corporation under public law and a legal entity, is one of the largest university hospitals in Europe. It represents the medical faculty of both Humboldt University Berlin and Free University Berlin, and is a corporate member of the Berlin Institute of Health. Clinical care, research and teaching are delivered by physicians and researchers of the highest international standard. Charité stands for modern medical training in Germany with high scientific standards and combines care, responsibility, respect and entrepreneurship in university medicine. Charité proudly lays claim to more than half of all German Nobel Prize winners in Physiology or Medicine, including Emil von Behring, Robert Koch, and Paul Ehrlich.

Contact:

Prof. Dr. med. Frank Mockenhaupt & Dr. med. Franziska Hommes
Charité-Universitätsmedizin Berlin
Institut für Tropenmedizin und Internationale Gesundheit
Campus Virchow-Klinikum
Augustenburger Platz 1
13353 Berlin
T: +49 30 450 565700
F: +49 30 450 565989
frank.mockenhaupt@charite.de
franziska.hommes@charite.de

International Health and University Teaching Hospital of Butare / Rwanda (CHUB)

CHUB is a 500-bed hospital located in the city of Huye in Rwanda’s Southern Province. It serves a population of over 3.7 million in the Southern Province plus some districts of the Western Province which are about 90% rural.
The pathology department (laboratory) of CHUB is the oldest in the country. During the colonial period, it was the only reference laboratory for Rwanda, Urundi (Burundi) and Congo Belge (Democratic Republic of Congo).
The pathology department of CHUB is the only one that can perform susceptibility testing in the Southern and Western Provinces.

Contact:

Djibril Mbarushimana MD, MMed
University of Rwanda
College of Medicine and Health Sciences
Head of Pathology Department at CHUB
Junior Lecturer at School of Medicine and Pharmacy
djidji01@gmail.com

MORE INFORMATION

ABOUT

Charité – Universitätsmedizin Berlin / Germany

Charité – Universitätsmedizin Berlin, a corporation under public law and a legal entity, is one of the largest university hospitals in Europe. It represents the medical faculty of both Humboldt University Berlin and Free University Berlin, and is a corporate member of the Berlin Institute of Health. Clinical care, research and teaching are delivered by physicians and researchers of the highest international standard. Charité stands for modern medical training in Germany with high scientific standards and combines care, responsibility, respect and entrepreneurship in university medicine. Charité proudly lays claim to more than half of all German Nobel Prize winners in Physiology or Medicine, including Emil von Behring, Robert Koch, and Paul Ehrlich.

Contact:

Prof. Dr. med. Frank Mockenhaupt & Dr. med. Franziska Hommes
Charité-Universitätsmedizin Berlin
Institut für Tropenmedizin und Internationale Gesundheit
Campus Virchow-Klinikum
Augustenburger Platz 1
13353 Berlin
T: +49 30 450 565700
F: +49 30 450 565989
frank.mockenhaupt@charite.de
franziska.hommes@charite.de

Logo Charite.svg 2

Internation Health and University Teaching Hospital of Butare / Rwanda (CHUB)

CHUB is a 500-bed hospital located in the city of Huye in Rwanda’s Southern Province. It serves a population of over 3.7 million in the Southern Province plus some districts of the Western Province which are about 90% rural.
The pathology department (laboratory) of CHUB is the oldest in the country. During the colonial period, it was the only reference laboratory for Rwanda, Urundi (Burundi) and Congo Belge (Democratic Republic of Congo).
The pathology department of CHUB is the only one that can perform susceptibility testing in the Southern and Western Provinces.

Contact:

Djibril Mbarushimana MD, MMed
University of Rwanda
College of Medicine and Health Sciences
Head of Pathology Department at CHUB
Junior Lecturer at School of Medicine and Pharmacy
djidji01@gmail.com

AMR Network
 AMR NETWORK 

Kumasi, Ghana – Hamburg

Asella, Ethiopia – Düsseldorf

Jimma, Ethiopia – Munich

Nairobi, KenYa – Frankfurt

Kampala, Uganda – Leipzig

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